- The Star-Spangled Banner
- Frida Kahlo's love letter to Diego Rivera
- Amelia Earhart's Lockheed Vega 5B
- Nat Turner's Bible
- An AIDS quilt panel honoring Roger Gail Lyon
- A signpost from the Standing Rock protest
- A glass-plate portrait of Abraham Lincoln
- Life-sized model of a Megalodon
- The Hope Diamond
- Chuck Berry's Cadillac
- Portrait of Henrietta Lacks
Py-Lieberman reflects on the profound connections between even outwardly dissimilar objects, and offers insight and stories from Smithsonian experts. The book explores artworks, scientific specimens, historical artifacts, airplanes, spacecraft, plants, and so much more, contemplating how each item represents different facets of humanity and resonates with cultural meaning in surprising ways. Whimsical, affecting, and insightful, The Object at Hand offers an intimate and exclusive tour of the Smithsonian collections.